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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
14.85
Human Site:
S200
Identified Species:
23.33
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
S200
E
K
H
S
L
D
A
S
Q
G
T
A
T
G
P
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
S200
E
K
H
S
L
D
A
S
Q
G
T
A
T
G
P
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
I169
S
P
E
P
Q
I
S
I
P
V
K
K
E
H
I
Dog
Lupus familis
XP_533153
501
54075
S200
E
K
H
A
L
D
A
S
Q
G
T
A
T
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
S200
E
K
H
S
L
D
A
S
Q
G
T
A
T
G
P
Rat
Rattus norvegicus
P08461
632
67147
P330
P
Q
P
L
A
P
T
P
S
A
A
P
A
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
T199
G
L
D
P
S
S
V
T
P
S
G
P
R
G
I
Frog
Xenopus laevis
NP_001087423
478
50485
I185
T
P
S
G
P
R
G
I
I
T
K
E
D
A
L
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
R193
L
R
L
S
P
A
A
R
H
I
L
D
T
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
R299
Q
V
Y
G
L
A
V
R
R
L
L
E
E
Y
G
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
I212
S
V
P
K
S
A
P
I
P
H
S
S
S
G
R
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
A187
G
L
S
P
A
V
R
A
L
I
D
Q
H
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
I297
D
A
E
S
I
E
A
I
K
S
S
S
A
G
S
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
S190
I
A
L
E
K
G
I
S
L
K
D
V
H
G
T
Red Bread Mold
Neurospora crassa
P20285
458
48601
A181
R
E
P
N
A
L
P
A
A
K
R
L
A
R
E
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
0
93.3
N.A.
100
13.3
N.A.
N.A.
6.6
0
20
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
100
6.6
100
N.A.
100
20
N.A.
N.A.
13.3
0
26.6
N.A.
N.A.
26.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
60
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
20
20
40
14
7
7
7
27
20
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
27
0
0
0
0
14
7
7
0
0
% D
% Glu:
27
7
14
7
0
7
0
0
0
0
0
14
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
14
0
7
7
0
0
27
7
0
0
60
14
% G
% His:
0
0
27
0
0
0
0
0
7
7
0
0
14
14
0
% H
% Ile:
7
0
0
0
7
7
7
27
7
14
0
0
0
0
20
% I
% Lys:
0
27
0
7
7
0
0
0
7
14
14
7
0
0
0
% K
% Leu:
7
14
14
7
34
7
0
0
14
7
14
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
7
14
20
20
14
7
14
7
20
0
0
14
0
0
34
% P
% Gln:
7
7
0
0
7
0
0
0
27
0
0
7
0
0
0
% Q
% Arg:
7
7
0
0
0
7
7
14
7
0
7
0
7
7
7
% R
% Ser:
14
0
14
34
14
7
7
34
7
14
14
14
7
0
7
% S
% Thr:
7
0
0
0
0
0
7
7
0
7
27
0
34
0
7
% T
% Val:
0
14
0
0
0
7
14
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _